Therapeutic dose

Hello Every body.
I have a question about therapeutic dose in cleaning validation for calculating the MACO of my Worst-Case Parenteral products. I search for it but because I’m a chemist and do not have enough knowelag about minimum and Maximum Therapeutic Dose of Lactated Ringer’s for Injection and Mannitol for Injection.
Pls answer me about this matter by valid references. I couldn’t find these.
Best Wishes