Tablet Lamination


Lamination is the term used for a split in the tablet anywhere but at the top. Lamination is essentially the same as capping and with similar causes. It is, nevertheless, important to diagnose the lamination issue correctly to ensure that proper steps are taken to solve the problem. Lamination often occurs due to the over compression of the tablet. Too much compression can lead to the granules flattening out and thus preventing them from locking together. This can also happen when light or fine particles do not combine, as these particles do not compress well. To prevent this, the thickness of the tablet needs to be reduced, and/or the dwell time increased to allow the fine particles to combine. To increase dwell time, pre-compression can be employed or the speed of the tablet machine can be reduced. Another option is to use a tapered die rather than a perfectly cylindrical die bore. Tapered dies generally do not exhibit capping or laminating problems.