Room pressure of aseptic filling area will be positive or negative?
positive in aseptic.bcz air moves from more classified to less classified to maintain area
What is used for smoke test of HEPA filter?
Basically purpose of Diff pressure is to prevent cross contaminaton.
there are 3 types of buffers
Bubble
Sink
Cascade
PAO does not generate smoke
PAO droplets are used for HEPA filter integrity test.smoke test is done to check laminarity of air flow.
o sorry i took it as aerosol smoke generation
In OSD we do not perform this test
is it req to chek laminarity in D Class?
A. Cascade Airlock: These airlocks are very common having a higher pressure on one side and lower pressure on another side. This prevents to enter dust and contaminants from outside to airlock and from airlock to inner side.
B. Bubble Airlock: These types of airlocks have a higher pressure inside the airlock and lower pressure in both outsides. This prevents the flow of air between two areas through the airlock creating a pressure barrier.
C. Sink Airlock: Airlocks having lower pressure inside the airlock and higher pressure on both sides of the airlock. This airlock pulls air from both adjacent areas creating a low-pressure barrier.
DOP(Di octyl phthalate) and PAO is two different aerosol.
Smoke test is required for HEPA filter( gradeA)
what is used for smoke generation?
Dried ice is used as smoke generator. It is used for checking the air flow pattern (laminar or turbulence).Laminar flow should be generated by HEPA .
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when we perform PAo test at which limit alarm beeps
How much gap is acceptable between HEPA filter surface and working height?
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No idea.
kindly explain?
0.01% leakage is acceptable.
mean whe alarm beeps reaxi g is .02?