R-LAF of dispensing area

Why we have to switch on R-LAF before 15 minutes of dispensing?

To replace the existing air which may contain non-viable particles, which leads to contamination during the sampling or dispensing…

Why differential pressure of the are is -ve with respect to the adjacent corridor for dispensing?

for containment (concept of clean corridor)

Which avoids contamination to corridor and adjacent areas…

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There is no specific reason for 15 minutes. It is generally recommended by the manufacturers of RLAF to start the system for about 15 minutes before actual dispensing or sampling operations to achieve a stable state (equilibrium in the air-filtration system).

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