how to validate blending process in process validation batches
it is necessary to withdrawn 10 point sampling at three different time (10 ,15 ,20 minutes at 15 RPM) when in BMR mentioned fix time (15 min at 15 RPM) of blending.
or
only withdrawn 10 point sample at mentioned time and speed in BMR (15 min at 15 RPM)
suggest me with any guideline referece