In Pre Filled Syringe system, During Formulation and filling, Nitrogen gas need for purging.
Nitrogen purging is done to prevent microbial growth.it is chemically inert gas.
Even though it is the rite answer. Nitrogen is technically not an inert gas. If you go by the general definition of inert gas. Nitrogen does changes it structures forming nitrous oxide etc. So it should not be included in noble gas.
PS: use of inert/noble described above are in the same contexts