The Polyproplene 0.2 micron cartridge filter is used to filter inject-able bulk. If it is not sterile by default then is it necessary to autoclave it before use or autoclaving will be required at the time of reuse of the cartridge filter?
Polypropylene Membrane Cartridges are highly retentive and constructed of naturally fine polypropylene fibres.Thease filters are specifically designed for use in applications where economy and reliability are critical. The polypropylene membrane is a reliable choice for the purification of aggressive chemicals, compressed gases, and vent applications. All materials of construction are FDA listed for direct food contact, and all components have been tested according to the USP Class VI biological tests for plastics at 121°C.
Sealing technology Thermal Bonding, No Adhesives , binders, or surfactants are used in the manufacturing process. Furthermore, the all-polypropylene construction provides excellent thermal and chemical compatibility with low and high pH
Features & Benefits
• Superior dirt-holding capacity & consistent particle removal performance
• High flow rates & low pressure drops
• Broad chemical compatibility & Provides excellent compatibility with a wide range of chemicals such as acids, bases, and solvents
• No adhesives, binders, or surfactants are used during manufacturing resulting in superior downstream cleanliness
• Low extractables and low protein binding
• All cartridges are rinsed with high-purity water to reduce extractables and downtime
Materials of Construction
• Media: Polypropylene Membrane (hydrophobic)
• Media Supports: Polypropylene
• Cage, Core, End Caps: Polypropylene
• O-Rings: Silicone, EPDM, Fluoroelastomer, Buna N, TES, TEV
• Diameter Φ68
• Length 5 inch, 10 inch, 20 inch, 30 inch & 40 inch.
Filtration Area, ft2
• 6 sq. ft.² per 10-inch cartridge
Pore Size, μm
• 0.1, 0.22, 0.45, 0.65, 1.0, 3.0, 5.0, 10, 20
Maximum Differential Pressure
• Forward: 4.8 bar @ 23 ℃; 1.5 bar @ 85 ℃
Sterilization & Autoclaving:
• The filters can be sterilized by autoclaving for up to 20 cycles at 125 °C (257 °F) for 30 minutes. The filters can also be sterilized by steam-in-place procedure up to 5 cycles at 135 °C (275 °F) for 30 minutes at less than 0.3 bar (4.35 psi) differential pressure. The filters can also sanitized by hot water or common chemicals that are compatible with filter components.
• Biologics PREFILTRATION
• Active Pharmaceutical Ingredients
• Primary process clarification
• DI and RO pretreatment
• Sugar syrup filtration
• Acids & Bases
• Fine Chemicals
• Plating Solutions
• Parts Cleaning
Thanks for the reply, pls brief about the cycles of autoclave i.e 20 cycles at 125 C etc…
Please be aware of what @Sajjad_Ahmad mentioned about numbers of cycles for autoclaving the PP filter is very specific to the manufacturer. Don’t take it as a general note.