Permitted daily exposure PDE

[Mustafa_M.farhan]

What is the PDE and how can we get the PDE value?

[Awad (Dr. Ahmed Mohamed Awad)]

Please see the following:

@Awad

https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-setting-health-based-exposure-limits-use-risk-identification-manufacture-different_en.pdf https://www.ema.europa.eu/en/documents/other/questions-answers-implementation-risk-based-prevention-cross-contamination-production-guideline_en.pdf

https://picscheme.org/docview/1947

https://www.who.int/medicines/areas/quality_safety/quality_assurance/QAS20_849_points_to_consider_on_cleaning_validation.pdf?ua=1