i want some information about package validation for HDPE canister
Basically you can include:
- Proper insertion of dessicant/cotton/rayon etc into bottle.
- Functioning all relevent sensors , its challenge test during different speed.
- Quality of your bottles, physical observation ,capping quality, leak tests, torque values.
4.Fill counts with respect to speed, min and max
5.Normal functioning of filling machine
- Downstream speed.
- All labeling checks and recording information
- All test as per inprocess checks of BPR.
Variable packaging process/Input materiel parameter would help us for HDPE type package validation.
Pack count (No of dosage form per bottle),
Type/size of closure,
No of desiccant(pouch/barrel form) per bottle,
However other than above mention variable, we need to check many challenge test for each & every step which have come cross for packaging process i.e. Filling , counting, desiccant inert, cotton insertion, torque value for opening and closing ,power % value etc.