OOS & OOT investigation tools & guideline

Which guideline follow in the investigation of oos and oot, and wht is the tool of investigation of oos and oot.

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MHRA & 6M Method shall be usefull to investigate

Investigation tool more used full is fishbone and 5 why method

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MHRA, Fishbone (ishikawa)

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Brain storming
Ishikawa method
6why
Method as appropriate use

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https://www.fda.gov/media/71001/download

please can someone share with us the SOP of OOS