Leak detection of bottles during process

The classical method of vacuum leak test using methylene blue is usually used for pharmaceutical blisters. I ask for testing bottles about 40 ml and 100ml. Can I use this method and how to determine if there is a leak or not.

You may use the same method as you have referred here. Alternatively, you can use simple method of inverting filled and sealed bottles. Piece of tissue paper should be wrapped on the mouth of sealed bottle. Keep inverted bottles for defined time interval and observe for any leakage. Tissue paper will become wet even if there is a slight leakage observed.


bubble emission method is suitable method for such application

based on ASTM D3078 - 02(2013) Standard Test Method

1 Like

Thank you very much

1 Like

thank you very much

You are welcome…