what is the key point to check during make the production plan in pharmaceutical indutries
Following aspects from GMP point of view should be considered while making production plan (layout) of the facility,
- Men & material movement (It should not be criss-crossed)
- Unilateral flow of activities / unit processes of production
- Minimise or no cross -contamination (Lay out and Air handlinf systems)
- Technical and Administrative measures to be taken to avoid cross-contamination
- Physical separation of areas of production, QC/QA, Utilities, Maintenance etc.
- Regulatory requirements