Integrity testing of vent filter

Water System
#1

What are the reasons of failure of a filter during imtegrity test?

#2

If filter housing remain leakage or loose connection, connection with integrity tester machine remain loose It’s help to failure integrity test. If use WFI and try again i think it pass but It’s not allow SOP.

#3

Please let us know the following information,

  • What is this filter? and its purpose?
  • Is it for filtration of a sterile product? or is it a vent filter fitted in the storage tank?
  • Is this hydrophilic OR hydrophobic type?
  • Have you received a Certificate of filter integrity from the manufacturer/supplier of this filter when newly purchased?
  • Is those for single use or multiple uses?
    -Did the integrity test fail before filtration OR after filtration of the solution/ product?
2 Likes
#4

All information is most important before filter integrity test.
I’m Added. It’s important Know flow rate and pressurized. Some filter flow rate 2.70ml/sec or 7.50ml/sec and pressure 1040mbar or other required. So before start programme need sure about this filter required programme.