How to calculate boiler requirements?

Can somebody please help me calculate the boiler requirements for my new pharma plant?
We have two 8.5 meter steam sterilizers, CIP/SIP systems to be used every 22 hrs in 2 FFS machines, 2 mixing tanks of 6000 ltr, 2 holding tanks of 3000ltr, a WFI Plant (which includes 2 MCDP of capacity 2000ltr/hr), and 2 or 3 garment autoclaves.

I would appreciate any help.

Thanks and Regards,