How determine previous product minimum daily dosage and subsequent product maximum daily dosage in MACO caluculation
For calculation of MACO why the subsequent product choosen for maximum daily dose?
@AsifHussain ı think your question is related with cleaning validation so it is always considered against worst case
This is the link for EMA (& PIC/S) guideline for setting limits (referred to in EU &PIC/S Annex 15)
This a link for Q & A on the previous guideline published by EMA