Friability test

Quality Control
1

what is the impotance of friability test?

2

1.To understand the shipping/ transportation withstanding capacity of product.
2.To have confidence level for coating stage.
3.To understand the product loss while handling

Thanks

3

yes more critical are
for
coating process aid
blistering aid
many friable tabs also break by movement of brushes during blistering

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4

Friability have an important parameter as its help us to evaluate the one of the most important parameter w.r.t. physical attribute over IH post compression stages(If any), post packaging in CCS, during transportation withstanding capacity of product over physical attribute.

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5

Right ,Exactly.
Could you please elaborate CCS!!

Thanks

6

Container closure system : A container closure system refers to the sum of the packaging components that together contain and protect the dosage form. This includes primary packaging components and
secondary packaging components, if the latter are intended to provide additional protection to the drug product.

The packaging system is equivalent to a container closure system.

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