Why filter is installed in WFI line of vial washing Machine?
It has been a common practice, though it is becoming less common recently, that vial washers use recirculated water in their operation.
For example, almos all vial washing machines operate in a cycle, where vials are rinsed with water and then dried, several times during the cycle. In order to reduce waste of water for injection (WFI), the first rinsing cycles are done using recirculated water from the final rinse (final rinse must be with WFI always, to reduce risk of vial contamination).
In summary, filters are installed in WFI line of washing machine to reduce the risk of particle contamination in the viales due to the use of recirculating water in the first rinsing.
The most common way to demonstrate that residual risk is acceptable is by qualifying the vial washing machine, taking samples and making sure that vials exiting the washer water meets requirements as of WFI
I hope this helps.
Thank you sir for you response, it is acceptable to install filter for recycled water but i want to know if WFI is already free from particles then why it needs to install filter for WFI wash