washing of coating pan afte enteric coating use of only food grade detergent is sufficient?
It all depends upon cleaning validation results which must meet acceptance criteria.
commonaly used materials?
Enteric coat polymers are difficult to wash.
usually they form hard layer difficult to remove with simple food grade detergents.
The hard layer is soften usually at basic ph so basic media is used.
NaOH 3-8 % is comonly used.
then effect of NaOH is neutralized using simple food grade detergents.
apart from NaOH different brands for enteric coat r also availble having basic ph.
What is the difference between food grade detergent and cleaning agents?
Please elaborate…
Thanks
Cleaning agents are substances (usually liquids, powders, sprays, or granules) used to remove dirt, including dust, stains, bad smells, and clutter on surfaces. Purposes of cleaning agents include health, beauty, removing offensive odor, and avoiding the spread of dirt and contaminants to oneself and others. Some cleaning agents can kill bacteria, e.g. on door handles, worktops and other metallic surfaces, and clean at the same time. Others, called degreasers, contain organic solvents to help dissolve oils and fats
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Acidic cleaning agents are mainly used for removal of inorganic deposits like scaling. The active ingredients are normally strong mineral acids and chelants. Often, surfactants and corrosion inhibitors are added to the acid.
Hydrochloric acid is a common mineral acid typically used for concrete. Vinegar can also be used to clean hard surfaces and remove calcium deposits. Sulphuric acid is used in acidic drain cleaners to unblock clogged pipes by dissolving greases, proteins, and even carbohydrate-containing substances such as toilet tissue.
They should be stored in cool dry areas away from sunlight, no higher than eye level
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Alkaline cleaning agents contain strong bases like sodium hydroxide or potassium hydroxide. Bleach (pH 12) and ammonia (pH 11) are common alkaline cleaning agents. Often, dispersants, to prevent redeposition of dissolved dirt, and chelants, to attack rust, are added to the alkaline agent.
Alkaline cleaners can dissolve fats (including grease), oils, and protein-based substances.
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Neutral washing agents are pH-neutral and based on non-ionic surfactants that disperse different types.
Degreaser
Cleaning agents specially made for removal of grease are called degreasers. These may be solvent-based or solvent-containing and metamorphic.
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well come bro
Why we use NaOH? Can we use other basic material?
basic detrgents contain NaOH or potasium hydroxide.
NaOH is most commonly used.
use of other basic detrgnts depend uopn results of cleaning validation
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Generally, the concept lies— if your products are acidic in nature, you have to select cleaning agent as basic in nature.
Thanks
enteric coat polymers are not wash able with acidic agents.