Differential Pressure in Manufacturing Area

Dear All ,

I want To know how Differential Pressure done for Cubicle , and Why it is different for different cubicle ???

Please Share Your knowledge regarding Differential pressure .


thanks sir for sharing info

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As we know that the differential pressure plays a important role in Controlling Contamination.

Differential pressure is adjusted as per the Air volume and Air balancing through HVAC systems.

Hence, for example: Generally for the Solid manufacturing area-Compression cubicle is less than the corridor pressure.
like wise for sterile filling area the-pressure is more than the adjacent area.

I agree with this information

Generally processing area has negative pressure with respect to clean corridor to avoid cross contamination of the product to adjacent processing area.
Accordingly exit air lock will have negative pressure with respect to processing area also to avoid cross contamination to the product.