Dear sir. Plz tell me about dissolution.
When use paddle or basket in analysis.
Plz reply me
Generally use basket in those tablets in which HPMC is using as a binder because if HPME will come to contract with water then it will show sticky correcter and the tablet in which HPMC is used as a binder will get swell and stick with vessel and drug is not release because tablet will not move properly but in basket tablet is in the center of the vessel and so drug will release continue.
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Thank you sir
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In Paddle Appratus tablet is dropped directly to the vessel and sample is mixed by the paddle in whole buffer but in Basket Appratus tablet is putted in a basket that has a specific mesh size through which sample released into the buffer.
It is a difference between Paddle & Basket Appratus also.
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