what is the difference b/w disintegrants and super disintegrants?
Disintegrants and super disintegrants are used to disintegrate the tab for better release and dissolution.
Disintegrants are conventional and have to use in high conc.
Super Dis are modified forms and are effective in low conc and give quick effects
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List disintegrants and super disintegrants…!
Disintegrants are
Stach
Cellulose
Super Dis are
Modified Starches e.g PGS
Sod starch glycolate
Cross carmeloose sod
Crosslinked PVP etv
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Pgs stands for…
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Pregelatinized starch
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Diff btw starch and pregeltanized starch…?
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stach is conventional not soluble in cold water.(25°c)
high qty used for disintegrents
PGS is modified starch form by cooking of starch and effective in less qty.
soluble in cold water
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Thnx sajjad sb
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