We have a non pharmacopoeial product Lycolate N 5ml (Glycopyrrolate 0.1mg/ml and Neostigmine methyl sulphate 0.5mg/ml)
We have to determine its BET limit.
But Glycopyrrolate injection limit mentioned in USP is 555.5 EU/mg
And neostigmine injection limit mentioned in JP is 5 EU/mg.
What will be BET limit of combine product of 5ml (Glycopyrrolate 0.1mg/ml and Neostigmine methyl sulphate 0.5mg/ml) .