what is the effect of coating pan speed on tablet coating?
Pan High speed & low spray rate:
-Chipping
-Picking
Pan Low Speed and high spray rate:
-Twining
-Logo bridging
how picking can occur at high pan and low spray rate?
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what should be the coating pan speed & pore size in coating bed?
Sticking and picking at high spray rate and low pan speed.
Agreed
yes now agreed.
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If high speed set to coat the dosage form it would create many coating defect i.e. Chipping,picking.
If low speed set to coat the dosage form it would create many defect i.e. twining,break line bridging, logo bridging
βPan speed was adjusted so as to ensure uniform mixing of tablet throughout the coating process in coating pan which is based on the tablet shape and size. Tablet film thickness depends upon the uniform mixing.β
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