1. What is the reason to perform micro swab sampling first prior to perform chemical swab sampling?

As a part of cleaning validation microbial aspects of cleaned equipment and efficiency of the cleaning procedure are very important aspects to be assessed. Micro-swab sampling is also performed to ascertain 'Cleaned equipment hold time".
In order to avoid contamination of the equipment surface during chemical swab sampling it is necessary to perform micro-swab sampling first to get true results.

Micro swab sampling is typically performed before chemical swab sampling for several important reasons in environments where cleanliness and contamination control are critical in pharmaceuticals. This sequential approach is designed to minimize the risk of contamination and to ensure the accuracy of chemical analysis.
Micro swab sampling is a critical first step in contamination control and quality assurance processes, as it identifies, removes, and prepares the surface for chemical swab sampling. This sequential approach helps maintain the integrity of the samples collected, ensures accurate results, and minimizes the risk of cross-contamination or interference from external factors.

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