Capping in tablets

1_How to repair Capping problem in tablets?
2_how differentiate between two different tablet which have the same shape ,color,thickness,hardness ?

First chk machine related
High pressure reduce hardness
high speed reduce speed
Tooling problem
Formulation related

over dried may add moisture
can chk slugging
low binder may increase binders

Many thanks

1 Like

other question Mr. Today in our department we made product consist two layers sustained and immediate . The operator mix sustained and immediate tablet in one bag .how to spearte each other sustained and immediate

mixed tabs r double layer or single layer sustain n single layer immediate?

if different can have same weigt?
same color?
same shape?

Single layer and same of the shape

Yes same

؟؟ …

  1. Check for the Logo…

Why you need to separate if its only one compressed tablet.

If its bilayer—if may be different size—Physically It cannot be separated----Deviation should be raised, investigation CAPA and --It should be disposed.


1 Like

Chemical test ?

one simple physical method is available but u will loss the tabs.
add all in water immediate relz will disintegrate n sustain relz will swell n become slippery due to polymer

can we consider the sticking issue like a cosmetic defect? this case is when the sticking appears on the engraving and we can still read the letters or numbers

some time can read letters n some time not

1.I think u MFD in diff molecule at diff color is not compress.
2.No colour means can issue .