Capping in tablets

Production
1

1_How to repair Capping problem in tablets?
2_how differentiate between two different tablet which have the same shape ,color,thickness,hardness ?

2

First chk machine related
High pressure reduce hardness
high speed reduce speed
Tooling problem
Formulation related

over dried may add moisture
can chk slugging
low binder may increase binders

3

Many thanks

1 Like
4

other question Mr. Today in our department we made product consist two layers sustained and immediate . The operator mix sustained and immediate tablet in one bag .how to spearte each other sustained and immediate

5

mixed tabs r double layer or single layer sustain n single layer immediate?

6

if different can have same weigt?
same color?
same shape?

7

Single layer and same of the shape

8

Yes same

9

؟؟ …

10
  1. Check for the Logo…
11

Dear,
Why you need to separate if its only one compressed tablet.

If its bilayer—if may be different size—Physically It cannot be separated----Deviation should be raised, investigation CAPA and --It should be disposed.

Thanks

1 Like
12

Chemical test ?

13

one simple physical method is available but u will loss the tabs.
add all in water immediate relz will disintegrate n sustain relz will swell n become slippery due to polymer

14

can we consider the sticking issue like a cosmetic defect? this case is when the sticking appears on the engraving and we can still read the letters or numbers

15

some time can read letters n some time not

16

1.I think u MFD in diff molecule at diff color is not compress.
2.No colour means can compress.no issue .