Is it permissible to process validation batches of different drug classes like hormones, lactams, cephalosporins, and general categories in the same GMP area under R&D, provided that due line clearance and all area cleaning procedures are followed according to SOP/Guidelines.
No, please. It is not permitted to manufacture different classes of drug products in the same GMP area. This is because of the possibility of cross-contamination of high-risk products into the general category products in the same area even if there are procedures of area, equipment cleaning, and line clearance in place.