Can area normalization calculation for Mass balance calculation?
if yes please give calculation procedure.
We can not consider to calculate mass balance through area normalization… all impurity must be quantify with use of external standard or diluted standard.
Mass balance can be calculate as below mentioned formula:
(Assay of degraded sample + total impurities generated)
Mass Balance = ------------------------------------------------------------------------------ X 100
(Assay of As Such sample + total impurities generated)