Pls tell me how to calculate the active with equivalent weight factor
Please clarify your question precisely.
Do you want calculation for conversion of API salt in to its equivalent base for adding into a batch of formulation?
Can you please illustrate your question with example?
Yes sir I have same question sir so pls tell me example
Please consider following calculations to convert API Salt in to its equivalent base for adding to the batch.
Amount of API Salt to be added into a batch (Kg) =
(Molecular weight of API Salt / Molecular weight of base of that API Salt) X Theoretical amount of API base to be added in the batch (Kg) as per label claim
For example, Quantity of Salbutamol Sulphate equivalent to Salbutamol base to be added in the batch as per label claim is as follows,
Amount of Salbutamol Sulphate to be added in a batch (Kg) =
(Molecular weight of Salbutamol Sulphate / Molecular weight of Salbutamol) X Theoretical amount of Salbutamol base to be added in the batch (Kg)
Thank u very much
You are always welcome.