How to calculate the bulk density of Tablets?
Bulk density of tablets required for that product which bulk /container pack will propose packaging configuration as market pack. Bulk density of tablet is ratio of a tablets (Mass) to its bulk volume (volume)
Measurement with graduated cylinder
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Take a 100 no of tablets & fill in 200 ml graduated cylinder.
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Note down the volume occupy 100 no of tablets.
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Calculate the BD by using following formula
Volume occupy for 100 no of tablets
BD = ------------------------------------------------
Total Volume of graduated cylinder.
Volume occupy for 100 no of tablets i.e. 122
Example BD = ----------------------------------------------------------
Total Volume of graduated cylinder i.e.200
= 0.61
For selecting the right container-closure system, we must evaluate the bulk density of tablets. Following key factor also play important role for bulk /container pack.
- Size of dosage form.
- Size & shape of container –closure.
- Manual hopper/Feeding pattern used for packaging product in CCS.
- The total volume of tablet and inter-particle void volume
density is
d=mass/volume
density of tab is taken as gm/ml
but in uper statement you yake just vol/vol .any ref,?