Beta and cepha block

Penicillin and cephalosporin both have beta lactam ring so why we need separate manufacturing block as beta block and cepha block?

Because of the potential health risks i.e. rashes, life-threatening anaphylaxis associated with cross-reactivity (cross-sensitivity) of betalactams, that’s why any manufacturers should assess and establish stringent controls (including appropriate facility design provisions assuring separation) to prevent cross-contamination.
Now say many regulatory authorities expects for manufacturers to treat sensitizing non-penicillin beta-lactam-based products similarly. Specifically, regulatory authorities recommends that manufacturers establish appropriate separation and control systems designed to prevent two types of contamination: (1) the contamination of a non-penicillin beta-lactam by any other non-penicillin beta-lactam, and (2) the contamination of any other type of product by a non-penicillin beta-lactam. Regulatory authorities recommends that the area in which any class of sensitizing beta-lactam is manufactured be separated from areas in which any other products are manufactured, and have an independent air handling system.

As with penicillin, the section of a facility dedicated to manufacturing a sensitizing nonpenicillin beta-lactam i.e. Cephalosporins, Monobactams, Penems, Carbacephems should be isolated (i.e., completely and comprehensively separated) from areas in the facility in which other products are manufactured. As with penicillin and non-penicillin beta-lactam drugs, such controls could include, but are not limited to, isolation and separation of intermediate and derivative materials, facilities, equipment, and personnel.

Note : About 2- 10% of people will be allergic to penicillin, which can trigger rashes, itchy eyes, and swollen tongue and face. In serious cases, an allergic reaction to penicillin can lead to difficulty breathing and anaphylactic shock, a potentially life threatening result of allergic reactions that can be fatal.

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Thanks for detail explanation