We have sugar coating process thas is not dissolving in 0.1N HCL for 1 hour. And after added buffer it dissolves in 5 minutes. We want to change this process to film coating or mixed sugar coating process. We tried it with mixed sugar coating process and f2 results are okay.
My question is should we check the f2 value when it is not dissolving in 0.1 N ? or is there specific term. For example 0.1 N it should not dissolve more than 10 percent.
Which way should i follow?