in test of cynoguandine in Metformin tablets , we have a problem in peak of metformin (big tailing ) in sample ,The problem has been addressed by making a sample dilution and changing of injection volume from 20 to 10 . Do we need a validation for the method?
yes, Definitely required.
I have available method for same as per you telling.
if you want then tell me.
yes we need this urgently