suitable procedure to prepapre coating susp?
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Aqueous system:
• Weigh the required quantity of coating materials
• Take the required quantity of boiled and cooled purified water in a stainless steel vessel. The temp. appox. 35°C to 40°C.
• Stir with propeller stirrer to form vortex. Add qty of coating materials individally in vortex, stir for 5 min.
• Reduce the speed of stirrer and continue for 40 minutes.
• Pass solution through 100 mash
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Solvent/ Non Aqueous system:
• Weigh the required quantity of coating materials
• Take required quantity of IPA in vessel.
• Stir with propeller stirrer to form vortex. Add qty of coating materials individally in vortex, stir for 10 min.
• Add quantity of Methylene Di-chloride and stir continue for 30-35 minutes.
• Pass the solution through 100 mash open sieve & amp; the material ready for use to coating the tablets.
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For some drug coating temp req is 70_80°C.
I want know which is drug name?
Sitagliptin phosphate for drug coating is soluble in hot water at 70-80 °C
In Non Aqueous system why IPA & MCL both solvent required?
only IPA CAN ALSO BE USED
than why MCL is also is used?
its may vary compny to compny formulations